PPIs in new fracture link
It’s the worst of both worlds: People who suffer from acid reflux now are at higher risk of bone breaks later.
But it’s not the condition that’s the problem — it’s the treatment. A new study again finds a link between proton pump inhibitors and bone breaks.
But who are we kidding here? The link between PPIs such as Prilosec, Nexium and Prevacid and brittle bones is so well known that the drugs even carry a warning label for it. Not that it has stopped docs from dishing them out left and right.
So while I doubt it will change a thing, let’s take a look at the new warning in the Annals of Family Medicine.
Korean researchers ran the numbers from 11 studies published since 1997 and found that people who take PPIs had a 29 percent increase in overall fracture risk — including a 31 percent increase in the risk of hip fractures and a 54 percent boost in the risk of vertebral fractures.
Again, no surprises here.
We even know why the drugs are so dangerous: They block the absorption of the calcium needed for healthy bone.
But calcium doesn’t work alone — it gets help from magnesium… and another recent study found that PPIs can block that, too.
And when it comes to magnesium deficiencies, fracture risk is only the beginning: People with low levels of this essential mineral also face muscle spasms, seizures, heart problems, and death.
Ready for the most outrageous part? These drugs don’t even work in the first place — because too much stomach acid is rarely the cause of stomach acid problems.
That may sound counterintuitive after years of commercials that show little cartoon stomachs bubbling over with acid, but the facts speak for themselves: Most people actually have too little stomach acid… not too much.
Suppressing it even further only leads to worsening heartburn, reflux and GERD down the road — which is why long-term PPI users ultimately experience a surge in symptoms, especially if they stop taking their meds.
For more on this, read Dr. Jonathan Wright’s groundbreaking book, “Why Stomach Acid Is Good for You.” You can get it from Amazon.com, a local bookstore, or even your library.
In the meantime, for some quick relief, try deglycyrrhizinated licorice or DGL (not to be confused with licorice candies).
Unlike PPIs, it can relieve your symptoms now without setting you up for more pain later.
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