For drug makers, it must have been a “you got your peanut butter in my chocolate” moment — but instead of “two great tastes that taste great together,” you’re about to get two bad meds that are even worse together.

The “peanut butter” in this case is the daily aspirin millions of heart patients are told to take — and taken by millions of others in the mistaken belief it can prevent those heart problems from happening in the first place.

The “chocolate” is omeprazole, aka Prilosec — part of a badly overused class of heartburn meds called proton pump inhibitors.

Now, I don’t have a problem with someone eating a little fresh-ground peanut butter, or even an occasional snack of dark chocolate.

But I have a big problem with people taking daily aspirin or proton pump inhibitors on a long-term basis — because both of these drugs come with huge health risks and minimal… to no… benefits.

Daily aspirin use isn’t nearly as beneficial as years and years of relentless marketing would have you believe. What’s more, it comes with a host of serious side effects such as bleeding problems, including ulcers, and even bleeding in the brain.

One of the milder but more immediate side effects, however, is heartburn — and that’s why the new peanut butter cup of pills mixes 325 mg of aspirin with the PPI omeprazole.

It’s supposed to prevent that heartburn and make it easier for people to take the daily aspirin. And to that extent, you could say it “works” — because PPIs are great at hiding the symptoms of heartburn and other stomach acid problems.

But PPIs also bring stomach acid to dangerously low levels.

In fact, the levels are so low that when you stop taking the drugs, the stomach tries to overcompensate and produces more acid than ever. Most people think it’s their acid problem coming back with a vengeance.

In reality, this “acid rebound,” as it’s called, is caused by the drug itself — and a reason many people can’t stop taking a PPI once they start.

PPIs can also block the absorption of key nutrients, leaving you seriously deficient in calcium, magnesium, vitamin D, vitamin C, and other essentials and putting you at risk for everything from bone breaks to death.

Pain, heartburn, and even cardiovascular health all have better and more natural answers. Work with your doctor to find them.

Your stomach is your best friend — yet millions of people treat it like their worst enemy.

They fill their guts with lousy food, and then at the first sign of heartburn or acid reflux, they carpet-bomb their bellies with dangerous drugs that not only won’t solve the problem… they can actually make it worse in the long run (while putting the rest of your body at risk to boot).

That’s no way to treat a friend!

Now, a leading consumer group is calling on the FDA to put black-box warnings on proton pump inhibitors such as Nexium, Prilosec and Prevacid because of all those risks — including the notorious “rebound” acid problems.

Public Citizen says people who take these meds often end up in a cycle of dependency: When they try to stop, that rebound kicks in — leaving them more miserable than ever. Eventually, what started as a short-term remedy becomes a lifelong addiction.

And even if the drugs manage to keep the reflux at bay for a little while, they’re slowly and silently doing far more damage in your gut than the drug industry will ever admit.

PPIs can destroy the delicate balance of stomach acid and gut bacteria, block the absorption of key vitamins and nutrients, and set you on a collision course for problems far worse than acid reflux.

Long-term use of these meds has been linked to severe and potentially deadly conditions such as magnesium deficiencies, heart problems, bone breaks, and infection.

PPIs can actually increase the risk of ulcers in hard-to-treat regions of the small intestine when taken with nonsteroidal anti-inflammatory drugs.

Despite all those risks, these are some of the nation’s best-selling meds. And the worst part? Most of the people who take them don’t even have the stomach conditions they’re prescribed for.

One recent study found that up to 70 percent of all PPI prescriptions are completely unnecessary. That number might sound high, but I’d say it’s more like 100 percent, because the fact is, you don’t need to turn to risky drugs to get your stomach under control.

Alternative medicine pioneer Dr. Jonathan Wright literally wrote the book on this. It’s called “Why Stomach Acid Is Good for You,” and the dozens of five-star reviews on Amazon.com should tell you everything you need to know about his advice.

Despite what you’ve heard, most people don’t have too much stomach acid — they have too little!

For more information, visit Dr. Wright’s website — and start treating your stomach like a friend again.

It’s the worst of both worlds: People who suffer from acid reflux now are at higher risk of bone breaks later.

But it’s not the condition that’s the problem — it’s the treatment. A new study again finds a link between proton pump inhibitors and bone breaks.

But who are we kidding here? The link between PPIs such as Prilosec, Nexium and Prevacid and brittle bones is so well known that the drugs even carry a warning label for it. Not that it has stopped docs from dishing them out left and right.

So while I doubt it will change a thing, let’s take a look at the new warning in the Annals of Family Medicine.

Korean researchers ran the numbers from 11 studies published since 1997 and found that people who take PPIs had a 29 percent increase in overall fracture risk — including a 31 percent increase in the risk of hip fractures and a 54 percent boost in the risk of vertebral fractures.

Again, no surprises here.

We even know why the drugs are so dangerous: They block the absorption of the calcium needed for healthy bone.

But calcium doesn’t work alone — it gets help from magnesium… and another recent study found that PPIs can block that, too.

And when it comes to magnesium deficiencies, fracture risk is only the beginning: People with low levels of this essential mineral also face muscle spasms, seizures, heart problems, and death.

Ready for the most outrageous part? These drugs don’t even work in the first place — because too much stomach acid is rarely the cause of stomach acid problems.

That may sound counterintuitive after years of commercials that show little cartoon stomachs bubbling over with acid, but the facts speak for themselves: Most people actually have too little stomach acid… not too much.

Suppressing it even further only leads to worsening heartburn, reflux and GERD down the road — which is why long-term PPI users ultimately experience a surge in symptoms, especially if they stop taking their meds.

For more on this, read Dr. Jonathan Wright’s groundbreaking book, “Why Stomach Acid Is Good for You.” You can get it from Amazon.com, a local bookstore, or even your library.

In the meantime, for some quick relief, try deglycyrrhizinated licorice or DGL (not to be confused with licorice candies).

Unlike PPIs, it can relieve your symptoms now without setting you up for more pain later.

Ask most doctors, and they’ll tell you that when it comes to gastroesophageal reflux disease (GERD), you have one of two choices: drugs or surgery. But a recent study should have them – and you – considering a third option.

After following patients for 12 years, the researchers determined that “both treatments leave room for therapeutic improvement.”

That’s one way of putting it. Of the patients who had surgery, only about 50 percent remained in remission, and only 40 percent of the patients on meds remained in remission.

But even then, postoperative difficulties had many patients trading one set of symptoms for another: heartburn and regurgitation for difficulties in swallowing, excessive flatulence, and the inability to belch or vomit. And to make matters worse, many of the surgery patients (38 percent) eventually had to go on drugs anyway.

If you think this makes acid-suppressing drugs like Prilosec look like the best possible option, you’re not the only one. Dr. Sutart Jon Spechler of the University of Texas Southwestern Medical Center in Dallas said, “I find it difficult to fathom why a typical GERD patient would opt for a potentially hazardous surgery to fix a problem managed almost as well by a reasonably safe medication.”

Of course you’d expect him to say that. The study was funded by AstraZeneca, the maker of Prilosec.

If this study was all you had to go by, you might come to the same conclusion. Fortunately, there’s plenty of other information on this drug.

For starters, Prilosec is only approved for short-term use. The manufacturer itself doesn’t recommend using beyond 14 days. Could that be because long-term use of the drug in rats led to an increase in gastroinstestinal cancers? Or maybe because it can cause joint, muscle, and leg pain? Or possibly it’s because of the diarrhea, abdominal pain, and nausea?

Whatever the reason, I can’t think of one person who only took this drug for 14 days. The study itself examined patients who had been taking it for 12 whole years! Even if patients tried to stop taking the drug, they’d be on it again before long because it doesn’t fix the problem. Once you stop taking it, all of your old symptoms are likely to flare up again in less than a week.

The bottom line is that drugs like Prilosec will come up short every time. It’s part of a class of drugs called proton pump inhibitors that work by reducing stomach acid to around 10 percent of normal levels. Problem is, you need stomach acid. And in reality, many of the people who have reflux problems are actually suffering from too little stomach acid – not too much. Which is why, as contradictory as this might sound, you should actually be looking for ways to increase your stomach acid levels.

One of the great pioneers of stomach acid is Dr. Jonathan Wright, and you can learn more on the real causes of heartburn, acid reflux and GERD from his website, www.wrightnewsletter.com. For a more detailed explanation – and a solution – pick up his book, “Why Stomach Acid Is Good for You.” It’s widely available from bookstores, online booksellers and libraries. v In the meantime, try some DGL, or deglycyrrhizinated licorice. You can find it in a vitamin shop or health food store, where it’s often sold as a chew. Just don’t confuse it with sugary licorice candies – they’re definitely not the same thing.

Many people who use DGL get the quick relief they’re looking for… with none of the problems of meds.